MonoMethylauristatin F(MMAF) CAS 745017-94-1

Product Description:

Product Name: MonoMethylauristatin F(MMAF) CAS NO: 745017-94-1

Synonyms:

(2S)-2-(2R,3R)-3-methoxy-3-(2S)-1-(3R,5S)-3-methoxy-5-methyl-4-methyl-(2S)-3-methyl-2-(2S)-3-methyl-2-(methylamino)butanoylaminobutanoylaminoheptanoylpyrrolidin-2-yl-2-methylpropanoylamino-3-phenylpropanoic acid;

Monomethyl auristatin phenylalanine;

Monomethylauristatin F;

Chemical Physical Properties:

Appearance: Solid powder

Assay : Greater than or equal to 99.0 percent

Density: 1.116±0.06 g/cm3 (20 degree 760 mmHg), Calc.

Water Solubility: Slightly soluble (2.8 g/L) (25 degree ), Calc.

Boiling Point: 896.8±65.0 degree (Predicted)

Storage temp.: Sealed in dry,Room Temperature

Vapour Pressure: {{0}}.0±0.3 mmHg at 25 degree

Index of Refraction: 1.522

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody.

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